1-脱氧野尻霉素及其衍生物生物活性研究进展

邓超,吴昭全,刘芳,曾光尧,周应军

中国药学杂志 ›› 2017, Vol. 52 ›› Issue (13) : 1110-1114.

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中国药学杂志 ›› 2017, Vol. 52 ›› Issue (13) : 1110-1114. DOI: 10.11669/cpj.2017.13.002
综述

1-脱氧野尻霉素及其衍生物生物活性研究进展

  • 邓超,吴昭全,刘芳,曾光尧,周应军*
作者信息 +

Progress in Research on Physiological Activity of 1-Deoxynojirimycin and Its Derivatives

  • DENG Chao, WU Zhao-quan, LIU Fang, ZENG Guang-yao, ZHOU Ying-jun*
Author information +
文章历史 +

摘要

1-脱氧野尻霉素是一种多羟基生物碱,具有降糖、降脂、抗肿瘤、抗病毒等众多生理功能。随着研究的深入,对相关生物活性的解释愈加清楚,并且在这一过程中不断有新的生理活性被发现。因此笔者对近年来与1-脱氧野尻霉素(及其衍生物)生物活性有关的新发现进行总结,为1-脱氧野尻霉素的进一步研究及应用提供参考。

Abstract

1-Deoxynojirimycin(DNJ), a polyhydroxylated alkaloid,has demonstrated numerous physiological activites, such as anti-diabetes, lipid-lowering,anti-cancer and anti-virus effects.As research continues, related activities have been explained even more clearly, and new physiological activities have been found. In this review, new discoveries of the physiological activities of DNJ and DNJ derivatives were summarized. This will provide pharmaceutical basis for future study and application of DNJ.

关键词

1-脱氧野尻霉素 / 降糖 / 抗病毒 / 降脂 / 衍生物

Key words

1-deoxynojirimycin / anti-diabetes / anti-virus / lipid-lowering / derivatives

引用本文

导出引用
邓超,吴昭全,刘芳,曾光尧,周应军. 1-脱氧野尻霉素及其衍生物生物活性研究进展[J]. 中国药学杂志, 2017, 52(13): 1110-1114 https://doi.org/10.11669/cpj.2017.13.002
DENG Chao, WU Zhao-quan, LIU Fang, ZENG Guang-yao, ZHOU Ying-jun. Progress in Research on Physiological Activity of 1-Deoxynojirimycin and Its Derivatives[J]. Chinese Pharmaceutical Journal, 2017, 52(13): 1110-1114 https://doi.org/10.11669/cpj.2017.13.002
中图分类号: R284   

参考文献

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国家科技十一五重大专项-新药创制项目
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